VITAMIN B6 INTAKE INVERSELY ASSOCIATED WITH RISK OF COLORECTAL CANCER
A meta-analysis of 13 prospective studies investigated the association of vitamin B6 intake with risk of colorectal cancer. Nine studies on vitamin B6 intake and four studies on blood pyridoxal 5’-phosphate (PLP) were included in the meta-analysis. An inverse association between vitamin B6 intake and blood PLP levels and the risk of colorectal cancer was found. Pooled analysis showed that the highest categories of vitamin B6 intake and blood levels of PLP were independently associated with a 10% reduced risk of colorectal cancer, compared with the corresponding lowest categories. Every 100-pmol/mL increase in blood PLP levels was associated with a 49% reduced risk of colorectal cancer. The authors of this study concluded, "Vitamin B6 intake and blood PLP levels were inversely associated with the risk of colorectal cancer in this meta-analysis.”
SOURCE: VitaSearch
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