Results from a cross-sectional Norwegian study involving 5,918 individuals (two groups, one 46-49 year olds and one 70-74 year olds) published in the American Journal of Clinical Nutrition found an inverse association between plasma choline concentrations and anxiety. Researchers collected information on the subjects’ plasma choline levels, and on their anxiety and depression symptoms. The authors observed a significant inverse association between plasma choline and anxiety levels alone (no significance for depression). The authors concluded that choline concentrations are negatively associated with anxiety symptoms.
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Abstract:
Summary: In a cross-sectional study involving 5,918 individuals (2 groups: 46-49 year olds and 70-74 years olds), an inverse association was observed between plasma choline concentrations and anxiety. Information on plasma choline levels and symptoms of anxiety and depression (Hospital Anxiety and Depression Scale) were collected. After adjusting for potential confounders, a significant inverse association was observed between plasma choline concentrations and anxiety levels alone (no significance found for depression). Thus, the authors of conclude, “In this large population-based study, choline concentrations were negatively associated with anxiety symptoms but not with depression symptoms.”
Source: “Choline in anxiety and depression: the Hordaland Health Study,” Bjelland I, Ueland PM, et al, Am J Clin Nutr, 2009, 90(4): 1056-60. (Address: Department of Child and Adolescent Psychiatry, Haukeland University Hospital, Bergen, Norway).
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